Off the top of my head, check that Photoshop has a decent amount of ram available to it in the preferences>performance, (mine uses about 2gb) and that scratch disks are properly set up - although by default it should be. If you have too many history states you might start running into problems too. Um, bit depth & resolution should be appropriate for the output intent.
Other than that, there is something wrong with your Photoshop installation?
Seen a couple of Quadro FX cards on tardme quite cheap, not really familiar with them & unless you are doing some serious high-end CAD work I really don't see the point personally.
Oh also perhaps look at this pdf, it was posted up on John Nack's blog recently (he is the Photoshop product manager and it's a really interesting and constantly updated blog if you are into that sorta stuff):
http://www.adobe.com/products/photoshop/photoshop/pdfs/pscs4_opt_performance.pdf