I think these guys have nailed it. I used it for PCs when I had 'em and they've just sent me an invite to the Mac trial.
http://www.backblaze.com/
This - from them - is gold.
quote:
Look, I'm an Advanced User, and I Already Have a Set of RAID Drives with Perl Scripts to Copy My Files Back and Forth Between My 18 Home Machines that are in a Datacenter I've Built in My Closet. Why Do I Need Backblaze?
Congratulations! It sounds like you're passionate about backup—and so are we. In fact, you may even want to send us a note on the jobs page. But we still think you should try Backblaze's online backup because it's automatic, will save your data remotely, and is really inexpensive.